The Young Children in Crisis Settings brief highlights the importance of supporting caregivers’ mental health in crisis settings to young children’s holistic development. It presents data on the severity of the global mental health crisis, which is being exacerbated by the lack of funding for psychosocial support for children, youth, and families. The brief focuses on why caregivers’ mental health matters in crisis settings and why it is critical to invest in and prioritize caregivers’ well-being and support in conflict and crisis-affected areas. It shares Illustrative examples of evidence-based interventions, that adopt a whole family approach to promote the mental health and psychosocial wellbeing of caregivers, responsive caregiving, and early learning; and how humanitarian workers promote and protect the mental health and psychosocial well-being of caregivers.